DeepMind Unveils AlphaGenome 2 to Predict Genetic Variant Effects Across Cell Types

DeepMind introduced AlphaGenome 2, an AI model trained on over 100 million single-cell profiles that predicts how genetic variants influence gene expression in hundreds of human cell types. The model nearly doubles the detection of impactful gene expression changes compared to its predecessor and can generalize to new cell types without retraining, supporting disease research and drug development.